Over 5000 delegates attended this year’s European Academy of Neurology congress in Vienna, Austria (25-28 June), and nearly 3000 joined online.
CGRP mAbs should be among first-line preventive treatments for migraine, with consideration given to which patients are most likely to benefit, levels of patient disability and medication costs. This was the broad consensus that emerged from a Controversies in Headache debate at the EAN 2022 congress, and it was in line with recommendations in the …
Read more »Eptinezumab treatment reduces monthly migraine days (MMDs) over weeks 1-12 of treatment compared to placebo in patients with episodic migraine (EM), chronic migraine (CM), medication overuse headache (MOH) or at least two previous treatment failures. These findings from exploratory analyses of selected sub groups of patients in the Phase 3b DELIVER trial of eptinezumab 100 …
Read more »Erenumab has shown sustained superior efficacy compared with standard of care (SOC) oral preventives in patients with episodic migraine (EM) who had previously failed one or two migraine preventives. Results of the APPRAISE global, prospective, randomised, open-label study in 621 patients with EM showed that a significantly higher proportion of patients stayed on erenumab at …
Read more »Daily headache was an exclusion criterion in registration trials of CGRP mAbs but is common in clinical practice. Results of a real world study of 47 patients with chronic migraine treated at the headache unit of a tertiary hospital have shown that patients respond to galcanezumab irrespective of whether they have daily headache. Patients had …
Read more »An interim analysis of data from the two-year Pan-European Real World (PEARL) prospective, observational study of fremanezumab has shown that 54.7% of patients with episodic or chronic migraine had a reduction in monthly migraine days (MMDs) of at least 50% over the six-month period from the start of treatment. Improvements were also seen in migraine-related …
Read more »Plasma CGRP levels more than doubled after six months treatment with erenumab, according to results of a study carried out in patients with migraine, the majority of whom had chronic migraine.1 In the 42 patients who took erenumab 70 mg for at least six months, the average number of headache days per month decreased from …
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Financial support was provided as GMG Knowledge Gap Grant from Pfizer Inc, Pfizer have provided only financial support and had no input into the content provided.
